Diane Simeone, MD

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Director of the Pancreatic Cancer Center
PhD, 1980 
University of California, Los Angeles
LAB WEBSITE:
Simeone Lab

Contact Information
NYU General Surgey Associates

160 East 34th Street, 9th Floor
New York, N.Y. 10016 

Tel.: (212) 731-6150

E-mail: diane.simeone@nyumc.org

Research Summary
Research Summary:
 
Diane Simeone is the Laura and Isaac Perlmutter Professor of Surgery and Pathology at New York University and the Director of the Pancreatic Cancer Center at NYU Langone Health.  She also serves as the Associate Director for Translational Research for the Perlmutter Cancer Center at NYU. She has been the recipient of numerous NIH grants (multiple R01s, U01, P50) investigating the molecular mechanisms driving pancreatic metastasis and the development of novel, more effective therapeutic strategies to treat pancreatic cancer patients. She also runs a large, multi-institutional research program focused on developing an early detection blood test for pancreatic cancer. She has served as President of both the Society of University Surgeons and the American Pancreatic Association. Dr. Simeone is currently the Chair of the National Scientific and Medical Advisory Board for the Pancreatic Cancer Action Network (PanCAN) and serves as the Principal Investigator on the Precision Promise Project, focused on developing a new national pancreatic cancer clinical trial infrastructure. She has served on the Board of Directors for the National Pancreas Foundation and on the Lustgarten Foundation Scientific Advisory Board, and is currently on the NCI Pancreatic Cancer Task Force and Early Detection Working Group. She is the recipient of the Randy Pausch Family Innovation Award (AACR), the Nina Braunwald Distinguished Professor Award (Harvard University), and the Chinese Society of Clinical Oncology Distinguished Investigator Award in Pancreatic Cancer. Dr. Simeone is a member of the National Academy of Medicine.
Selected Publications: 
·Definitive Chemoradiation With Full-dose Gemcitabine for Unresectable Pancreatic Cancer: Efficacy of Involved-Field Radiotherapy Zhou, Jessica; Fang, Charles X; Shen, Jincheng; Schipper, Matthew J; Zalupski, Mark M; Minter, Rebecca M; Simeone, Diane M; Hart, Deanna; Eagle, Taylor; Kimmel, Grace W; Vainshtein, Jeffrey; Lawrence, Theodore S; Feng, MaryAmerican journal of clinical oncology. 2017 Oct . 40 (5): 517-522
·High-Throughput Microfluidic Labyrinth for the Label-free Isolation of Circulating Tumor Cells  Lin, Eric; Rivera-Baez, Lianette; Fouladdel, Shamileh; Yoon, Hyeun Joong; Guthrie, Stephanie; Wieger, Jacob; Deol, Yadwinder; Keller, Evan; Sahai, Vaibhav; Simeone, Diane M; Burness, Monika L; Azizi, Ebrahim; Wicha, Max S; Nagrath, SunithaCell systems. 2017 Sep 27. 5 (3): 295-304.e4
·Microfluidic continuum sorting of sub-populations of tumor cells via surface antibody expression levels  Jack, Rhonda; Hussain, Khadijah; Rodrigues, Danika; Zeinali, Mina; Azizi, Ebrahim; Wicha, Max; Simeone, Diane M; Nagrath, SunithaLab on a chip. 2017 Mar 29. 17 (7): 1349-1358